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Diagnosis of drug-resistant TB and provision of second-line TB treatment in India: some ethics considerations 
Indian Journal of Medical Ethics 
Jerome Amir Singh, Anant Bhan, Ross Upshur 

In anticipation of the impending publication of the third phase of India’s Revised National Tuberculosis Control Program (RNTCP), members of our Ethical, Social, and Cultural Program for Global Health have published a paper exploring India’s ethical obligations with respect to the detection and treatment of tuberculosis (TB). Jerome Singh, Anant Bhan, and Ross Upshur argue that India must seize its current opportunity to revolutionize TB management and stem its growing crisis of TB morbidity and mortality through nation-wide deployment of new, rapid TB diagnostic tools such as the GeneXpert® MTB/RIF test. Since the Xpert test has demonstrated sensitive detection of TB and of resistance to first-line therapeutics (i.e., Rifampicin), the authors also consider India’s ethical obligation to provide universal access to second-line TB drugs for those diagnosed with first-line resistance, in light of the WHO’s Guidance on ethics of TB prevention, care, and control (published November 2010).

For full access to this article, please click HERE.

For further information, please contact Jerome Singh at:

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The Sandra Rotman Centre is based at the University Health Network and University of Toronto. We develop innovative global health solutions and help bring them to scale where they are most urgently needed. The Sandra Rotman Centre hosts Grand Challenges Canada, the Ethical, Social and Cultural (ESC) Program for Global Health and the Sandra Rotman Laboratories.

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