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December 23, 2014
Life-Saving Stem Cells - Discover, Learn, Share
 Jessica McCabe, Holly Kinder, and Emily Wyatt of the WEST LAB, are the 2014 ADS/RBC "Decorate your Door for Christmas" winners! The 3rd floor office door was designed to mirror that of a functional photo booth.  Complete with choice of a "selfie" removable Santa or Elf,  face-hole-board. 
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More RBC Office Doors:
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Mary Alice Smith
Dose-Response of Listeria monocytogenes Invasion, Fetal Morbidity, and Fetal Mortality after Oral Challenge in Pregnant and Non-Pregnant Mongolian Gerbils (Meriones unguiculatus)

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Shelley Hooks and Stice
Convergent regulation of neuronal differentiation and Erk and Akt kinases in human neural progenitor cells by lysophosphatidic acid, sphingosine 1-phosphate, and LIF: specific roles for the LPA1 receptor.

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Maria M. Viveiros
Depletion of pericentrin in mouse oocytes disrupts microtubule organizing center function and meiotic spindle organization.

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Shanta Dhar Awarded:
Thieme Chemistry Journal Awardee for 2015. The award is intended to recognize promising young professors at the beginning of their career. This award, established in 1999 with the aim to encourage young scientists, is granted to prospective chemists who have been recognized as high-potential researchers in the field of synthetic organic chemistry by the editorial board members of SYNTHESIS, SYNLETT and SYNFACTS.

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Regenerative Bioscience Center
RBC Invited to Speak in Nanning China
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Athens, GA – UGA Regenerative Bioscience members, Franklin West and Steven Stice traveled on behalf of the Jun Wu Forum to Guangxi University in Nanning China as invited guest speakers.  Dedicated to Jun Wu, a celebrated scientist and educator in China and first president of Guangxi University, the forum invites distinguished scientist worldwide, and is part of an ongoing collaboration between Guangxi and the University of Georgia.

Stice presented the inner workings of start-up compchina3anies.  In detail, he covered the importance of having a great idea, the development of disruptive technology and how to target specific markets. Stice used examples from several of his own successful start-up companies including; ArunA Biomedical and Advanced Cell Technologies.

West talked about the use of stem cells for the development of transgenic animals. “Induced pluripotent stem cells have the potential to enable the development of animals with complex genetic modifications that improve important agricultural traits such as marbling in beef cows and the number of eggs producechina2d by chickens. In addition, this technology can be more useful in making predictive animal models of human diseases,” echoed West. He also noted that induced pluripotent stem cells in species such as the pig, will allow important stem cell therapy questions to be addressed in the same species from which they were derived.

While visiting, West and Stice were able to tour the cutting edge facilities of the State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources and the Animal Reproduction Institute.cave

Upon returning State side, from their brief sixty-hour flight, to their thirty-six-hour whirlwind land tour, the pair somehow managed to enjoy a breathtaking, limestone cave with a quick stop at Tiananmen Square and Olympic park, the original site of the 2008 Olympics.
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UGA researchers work to develop stem cell bank for Sumatran tiger, clouded leopard

tiger Their biggest hurdle now is funding, and they're using UGA's new crowdfunding initiative, known as the GeorgiaFunder, to collect resources for their project.

Wild animals such as the Sumatran tiger and clouded leopard are threatened as a result of climate change, habitat loss and other consequences of human activities, as well as poaching and urban development. It is estimated that between 500-600 Sumatran tigers remain in the wild, and the actual number may be as low as 400.

Stem cell technology provides hope for these endangered species. Using a novel stem cell technology pioneered by West and Stice, stem cells can be generated from skin cells. These cells can then be turned into sperm for artificial insemination in zoo breeding programs.
Details on how you can support this project
 
ELSEVIER
 
  • Journal of the Mechanical Behavior of Biomedical Materials, RBC member Zion Tse Mechanical properties and phase transition of biomedical titanium alloy strips with initial quasi-single phase state under high-energy electropulses
  • Mitochondrial Medicine: Methods and Protocols, Volume II: Manipulating Mitochondrial Function describes techniques developed for manipulating and assessing mitochondrial function under general pathological conditions and specific disease states., RBC member Shanta Dhar Formulation and Optimization of Mitochondria-Targeted Polymeric Nanoparticles
RBC Member William S. Kisaalita: Concave cylindrical surface induced cell peeling

Kisaalita Kisaalita, We have developed a PDMS pattern with arrays of microwells for the formation of multicellular aggregates by C17.2 neural stem cells. The induction of aggregate formation by the pattern takes advantage of cell peeling on concave microwell sidewall surfaces after cellular strip formation. The resulting aggregates were suspending in microwells with tethering to the pattern and thus have effective mechanical support for withstanding regular culture handling. Within the structural dimensions tested, we found that a small microwell diameter and a narrow channel width would facilitate the aggregate induction by the pattern and thus the D80-W20 and D100-W20 patterns were considered to be the most favorable patterns for aggregate formation by C17.2 cells. VIEW




 
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